Welcome to the

Pascoal Lab

About the

Lab

Our lab is interested in the quantification of brain pathophysiology in patients with Alzheimer’s disease (AD) and related dementias as well as in the validation of therapies capable of modifying the course of these diseases producing an enduring disease-modifying and clinically relevant effect. This involves the validation of positron emission tomography (PET) and fluid biomarker techniques capable of measuring these brain pathologies and monitoring their progression.

Research in

Focus

Recent

Publications

The Lancet

Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer’s disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study

Jama Neurology

A Harmonized Visual Reading Framework for Tau PET Staging in Alzheimer Disease

Molecular Neurodegeneration

Astrocyte reactivity identifies p-tau217-positive individuals at elevated risk of cognitive decline across the Alzheimer’s disease continuum

The Lancet

Alzheimer’s disease

The Lancet Medical Imaging & Theranostics

Low-dose CT for MRI-free quantification of tau PET in Alzheimer’s disease: a multicentre, cross-sectional, comparison study

Jama Network

Age at Diagnosis and Clinical and Genetic Profiles Among Adults With Attention-Deficit/Hyperactivity Disorder

Funding

Affiliations

Funding

Affiliations