Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease.
Zhang H, Therriault J, Kang MS, Ng KP, Pascoal TA, Rosa-Neto P, Gauthier S; Alzheimer’s Disease Neuroimaging Initiative.
Alzheimers Res Ther. 2018 Aug 16;10(1):80. doi: 10.1186/s13195-018-0407-6.
In vivo quantification of neurofibrillary tangles with [18F]MK-6240.
Pascoal TA, Shin M, Kang MS, Chamoun M, Chartrand D, Mathotaarachchi S, Bennacef I, Therriault J, Ng KP, Hopewell R, Bouhachi R, Hsiao HH, Benedet AL, Soucy JP, Massarweh G, Gauthier S, Rosa-Neto P.
Alzheimers Res Ther. 2018 Jul 31;10(1):74. doi: 10.1186/s13195-018-0402-y.
Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer’s disease.
Pascoal TA, Mathotaarachchi S, Shin M, Park AY, Mohades S, Benedet AL, Kang MS, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.
Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):1021-1030. doi: 10.1007/s00259-018-3933-3. Epub 2018 Feb 2.
Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?
Gauthier S, Zhang H, Ng KP, Pascoal TA, Rosa-Neto P.
Transl Neurodegener. 2018 May 31;7:12. doi: 10.1186/s40035-018-0117-9. eCollection 2018.
Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.
Therriault J, Ng KP, Pascoal TA, Mathotaarachchi S, Kang MS, Struyfs H, Shin M, Benedet AL, Walpola IC, Nair V, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.
Neurology. 2018 Mar 13;90(11):e932-e939. doi: 10.1212/WNL.0000000000005120. Epub 2018 Feb 14.
CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.
Neurol Genet. 2018 Jan 30;4(1):e216. doi: 10.1212/NXG.0000000000000216. eCollection 2018 Feb.
Targeting Alzheimer’s Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment.
Gauthier S, Ng KP, Pascoal TA, Zhang H, Rosa-Neto P.
J Alzheimers Dis. 2018;64(s1):S23-S31. doi: 10.3233/JAD-179924.
Identifying incipient dementia individuals using machine learning and amyloid imaging.
Mathotaarachchi S, Pascoal TA, Shin M, Benedet AL, Kang MS, Beaudry T, Fonov VS, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.
Neurobiol Aging. 2017 Nov;59:80-90. doi: 10.1016/j.neurobiolaging.2017.06.027. Epub 2017 Jul 11.
Author response: Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.
Gauthier S, Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedetti AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P.
Neurology. 2017 Oct 31;89(18):1931. doi: 10.1212/WNL.0000000000004593.