Astrocytes, cells that are involved in the brain’s support system, might play an important role in the progression of Alzheimer disease, according to results from 1016 participants with and without amyloid-β pathology who were all cognitively unimpaired....
Why do some people with amyloid plaques decline, while others do not? In the May 29 Nature Medicine, researchers led by Tharick Pascoal at the University of Pittsburgh laid some of the blame on reactive astrocytes. Among cognitively healthy people with amyloid...
Tharick Pascoal, MD, PhD (Associate Professor of Psychiatry) is an internationally recognized expert on the imaging and fluid biomarkers of Alzheimer’s disease and related dementias. He recently published two papers examining the multifaceted but interactive...
A blood test that can detect people at early risk of Alzheimer’s is a step closer after scientists implicated a key brain cell in the development of the disease. As well as providing the basis for a test, their work points to a resolution of one of the persistent...
Scientists may have found the true cause of Alzheimer’s disease — and believe the condition can be detected using a simple blood test. Experts have long known the build-up of amyloid in the brain is linked to the disease, but whether the plaques are a...
Department of Psychiatry investigators focused on Alzheimer’s Research—Victor Villemagne, MD (Professor of Psychiatry); Tharick Pascoal, MD, PhD (Associate Professor of Psychiatry and Neurology); and Thomas Karikari, PhD (Assistant Professor...
