Do microglia thwart neurodegenerative disease, or help it along? Do they keep amyloid in check with one hand, while goading tau entanglement with the other? Do they protect neurons early on in disease, but sour into synaptic slayers later? As the field gears up to...
We are delighted to announce that Tharick Pascoal, MD, PhD, has been promoted to Associate Professor of Psychiatry by the University of Pittsburgh School of Medicine. Dr. Pascoal received his MD from Federal University of Pelotas in Brazil. He...
Having a genetic predisposition to attention-deficit/hyperactivity disorder, or ADHD, is associated with cognitive decline and may predict Alzheimer’s disease in old age, early research released Thursday suggests. Recent large studies have hinted at a link...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition that affects 2.5% of adults worldwide. Pharmacotherapy is the recommended initial treatment for most adults, but patient adherence can be low due to adverse effects and other concerns....
In Alzheimer’s disease, reactive astrocytes can play an important role in the pathophysiology of the disease. Amyloid-β and tau tangles—the two main pathological hallmarks of Alzheimer’s disease—are associated with astrocyte reactivity. However, knowledge about...
The National Institute on Aging (NIA) has awarded the University of Pittsburgh Department of Psychiatry a Program Project Grant (PPG) renewal for “The role of astrogliosis in aging and the pathological and clinical progression of Alzheimer’s disease.” The...
